Nanomaterials Based Multifunctional Bioactivities of V 2 O 5 and Mesoporous Carbon@V 2 O 5 Composite: Preparation and Characterization.
Sneha R BhosaleRakhee R BhosaleRushikesh P DhavaleGovind B KolekarVinod B ShimpalePrashant V AnbhulePublished in: Langmuir : the ACS journal of surfaces and colloids (2024)
Nanocarriers have attracted considerable interest due to their prospective applications in the delivery of anticancer medications and their distinct bioactivities. Biogenic nanostructures can be effective nanocarriers for delivering drugs as a consequence of sustainable and biodegradable biomass-derived nanostructures that perform specific functions. In this case, a vanadium oxide (V 2 O 5 ) and mesoporous carbon@V 2 O 5 (C@V) composite was developed as a possible drug delivery system, and its bioactivities, including antioxidant, antibacterial, and anticancer, were investigated. Doxorubicin (DOX), an anticancer drug, was introduced to the nanoparticles, and the loading and release investigation was conducted. Strong interfacial interactions between mesoporous carbon (MC) and V 2 O 5 nanostructures have been found to improve performance in drug loading and release studies and bioactivities. After incubation, the potent anticancer effectiveness was seen based on C@V nanocomposite. This sample was also utilized to research potential biomedical uses as an antioxidant, antibacterial, and anticancer. The most effective antioxidant, the C@V sample (61.2%), exhibited a higher antioxidant activity than the V-2 sample (44.61%). The C@V sample ultimately attained a high DOX loading efficacy of 88%, in comparison to a pure V 2 O 5 sample (V-2) loading efficacy of 80%. Due to the combination of mesoporous carbon and V 2 O 5 , which increases specific surface area and surface sites of action as well as the morphology, it proved that the mesoporous carbon@V 2 O 5 composite (C@V) sample demonstrated greater efficacy.
Keyphrases
- drug delivery
- anti inflammatory
- oxidative stress
- cancer therapy
- metal organic framework
- highly efficient
- drug release
- ionic liquid
- silver nanoparticles
- climate change
- molecular dynamics simulations
- quantum dots
- adverse drug
- high resolution
- wound healing
- electronic health record
- carbon nanotubes
- atomic force microscopy
- essential oil
- anaerobic digestion
- case control