Excision of a gastrointestinal stromal tumour in a dog using short-wave infrared fluorescence imaging and indocyanine green.
Jinyoung ChoiSungin LeePublished in: Veterinary medicine and science (2024)
A 7-year-old castrated male Golden Retriever weighing 36.8 kg presented to the Veterinary Teaching Hospital with vomiting, anorexia and depression. After blood tests, radiographic, ultrasound and computed tomography examinations, a 7.85 × 5.90 × 8.75 cm mass was identified in the caecum. To visualise the tumour margin and improve the accuracy of tumour resection, intraoperative short-wave infrared imaging using indocyanine green was performed during surgery. An indocyanine green solution was injected intravenously as a bolus of 5 mg/kg 24 h before surgery. Tumour resection was performed with a 0.5 cm margin from the fluorescent-marked tissues. Histopathological examination revealed a diagnosis of a gastrointestinal stromal tumour (GIST) and the absence of neoplastic cells in the surgical margin, indicating a successful surgery. To our knowledge, this is the first case of a GIST resection in a dog using intraoperative short-wave infrared imaging.
Keyphrases
- fluorescence imaging
- minimally invasive
- coronary artery bypass
- computed tomography
- high resolution
- surgical site infection
- healthcare
- induced apoptosis
- patients undergoing
- depressive symptoms
- gene expression
- coronary artery disease
- magnetic resonance
- cell cycle arrest
- single cell
- oxidative stress
- mass spectrometry
- endoplasmic reticulum stress
- abdominal pain