Effect of next-step antidepressant treatment on suicidal ideation: findings from the VAST-D trial.
Sidney ZisookChristine Yu MoutierAugustus John RushGary R JohnsonIlanit TalPeijun ChenLori L DavisPaul B HicksJames WilcoxBeata PlanetaKimberly Weingart LauroAlexandra A ScrymgeourJohn KasckowSomaia MohamedPublished in: Psychological medicine (2023)
SI declines for most patients during next-step medication treatments. But about 1 in 5 experienced emergent or worsening SI during treatment, so vigilance for suicide risk through the entire 12-week acute treatment period is necessary. Treatment selection may affect the risk of SI.
Keyphrases
- end stage renal disease
- clinical trial
- healthcare
- major depressive disorder
- chronic kidney disease
- ejection fraction
- intensive care unit
- combination therapy
- study protocol
- peritoneal dialysis
- acute respiratory distress syndrome
- respiratory failure
- ionic liquid
- hepatitis b virus
- adverse drug
- open label
- smoking cessation