Effect of increased levothyroxine dose on depressive mood in older adults undergoing thyroid hormone replacement therapy.

Jae Hoon MoonJi Won HanTae Jung OhSung Hee ChoiSoo LimKi Woong KimHak Chul Jang

Published in: Clinical endocrinology (2020)

Depressive mood improves with increased LT4 dose, without significant hyperthyroid symptoms or signs, in older adults undergoing thyroid hormone replacement. These findings suggest the potential for varying the treatment target for hypothyroidism based on mood status and that low-dose LT4 treatment might be an ancillary treatment for depression.

Keyphrases

replacement therapy
bipolar disorder
low dose
sleep quality
physical activity
depressive symptoms
risk assessment
smoking cessation
combination therapy
climate change
human health