Association between mutational subgroups, Warburg-subtypes, and survival in patients with colorectal cancer.
Kelly OffermansJosien C A JenniskensColinda C J M SimonsIryna V SamarskaGregorio E FazziJaleesa R M van der MeerKim M SmitsLeo J SchoutenMatty P WeijenbergHeike I GrabschPiet A van den BrandtPublished in: Cancer medicine (2022)
Our results highlight the prognostic potential of mutational subgroups in CRC. Warburg-subtypes did not provide additional prognostic information within these mutational subgroups. Future larger-scale prospective studies are necessary to validate our findings and to examine the potential clinical utility of CRC subtyping based on mutational subgroups.