Impact of Mineralocorticoid Receptor Gene NR3C2 on the Prediction of Functional Classification of Left Ventricular Remodeling and Arrhythmia after Acute Myocardial Infarction.
Rima BraukylieneAli AldujeliAyman HaqLaurynas MaciuleviciusDarija JankauskaiteMartynas JurenasRamunas UnikasVytautas ZabielaVaiva LesauskaiteSandrita SimonyteDiana ZaliaduonytėPublished in: International journal of environmental research and public health (2022)
SNPs of the NR3C2 gene appear to correlate with better ventricular remodeling and a reduced rate of arrhythmias post-AMI, possibly by limiting the deleterious effects of cortisol on cardiomyocytes.
Keyphrases
- acute myocardial infarction
- left ventricular
- genome wide
- copy number
- percutaneous coronary intervention
- heart failure
- hypertrophic cardiomyopathy
- genome wide identification
- machine learning
- cardiac resynchronization therapy
- mitral valve
- deep learning
- aortic stenosis
- catheter ablation
- left atrial
- acute coronary syndrome