A graph neural network-based interpretable framework reveals a novel DNA fragility-associated chromatin structural unit.
Yu SunXiang XuLin LinKang XuYang ZhengChao RenHuan TaoXu WangHuan ZhaoWeiwei TuXuemei BaiJunting WangQiya HuangYaru LiHebing ChenHao LiXiaochen BoPublished in: Genome biology (2023)
Our study provides a more systematic and refined view enabling a better understanding of the mechanisms of DSB formation under the context of the 3D genome.