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Immune response dynamics and Lutzomyia longipalpis exposure characterize a biosignature of visceral leishmaniasis susceptibility in a canine cohort.

Manuela da Silva SolcàMaiara Reis ArrudaBruna Martins Macedo LeiteTiago Feitosa MotaMiriam Flores RebouçasMatheus Silva de JesusLeila Denise Alves Ferreira AmorimValéria Matos BorgesJesus G ValenzuelaShaden KamhawiPatrícia Sampaio Tavares VerasDeborah Bittencourt Mothé FragaClaudia Ida Brodskyn
Published in: PLoS neglected tropical diseases (2021)
The biosignature identified in our study reinforces the idea that CVL is a complex multifactorial disease that is affected by a set of factors which are correlated and, for a better understanding of CVL, should not be evaluated in an isolated way.
Keyphrases
  • immune response
  • toll like receptor