Retinal vascular density as a potential biomarker of diabetic cerebral small vessel disease.
Yinqiong HuangSiyun WangChi CaiXinwei HuangYan ChenXiaohong WuYiping ZhangYan ZhangXiahong LinPublished in: Diabetes, obesity & metabolism (2024)
Diabetic CSVDs are characterized by MRI markers, including deep WMHs and cerebral microbleeds, and showed impaired cognition with decreased visuospatial/executive ability and delayed recall ability. OCTA imaging revealed a significant decrease in retinal microvascular perfusion in diabetic CSVD, which was related to MRI markers and cognitive function. OCTA might be a valuable potential measurement for the early diagnosis of CSVD.
Keyphrases
- contrast enhanced
- type diabetes
- wound healing
- magnetic resonance imaging
- optical coherence tomography
- diabetic retinopathy
- working memory
- subarachnoid hemorrhage
- computed tomography
- optic nerve
- magnetic resonance
- cerebral ischemia
- multiple sclerosis
- brain injury
- blood brain barrier
- white matter
- risk assessment
- climate change
- cerebral blood flow