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Analysis of common cytogenetic abnormalities in New Zealand pediatric ALL shows ethnically diverse carriage of ETV6-RUNX1, without a corresponding difference in survival.

Tristan PettitNyree ColeWingchi LeungKirsten BallantineScott Macfarlane
Published in: Pediatric blood & cancer (2017)
A lower frequency of the favorable prognostic marker ETV6-RUNX1 was observed in Maori pediatric ALL patients. This did not translate into poorer survival. Future research into biological and nonbiological prognostic factors in this patient population may assist in explaining this finding.
Keyphrases
  • prognostic factors
  • acute lymphoblastic leukemia
  • end stage renal disease
  • transcription factor
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • peritoneal dialysis
  • free survival