Heme Oxygenase-1 Reduces Sepsis-Induced Endoplasmic Reticulum Stress and Acute Lung Injury.

Xiaozhen ChenYinglin WangXiang XieHongfei ChenQiqi ZhuZhidong GeHua WeiJingshong Deng Zheng-Yuan Xia Qingquan Lian

Published in: Mediators of inflammation (2018)

ER stress was activated during CLP-induced ALI, which may represent a mechanism by which CLP induces ALI. HO-1 activation could inhibit CLP-induced lung ER stress and attenuate CLP-induced ALI.

Keyphrases

high glucose
endoplasmic reticulum stress
diabetic rats
drug induced
intensive care unit
endothelial cells
lipopolysaccharide induced
cell proliferation
lps induced