Reactive Oxygen Species Are Essential for Vasoconstriction upon Cold Exposure.

Di Zhang Shiquan ChangBei JingXin LiHuimei ShiYachun ZhengYi LinZhenni ChenGuoqiang QianYuwei PanGuoping Zhao

Published in: Oxidative medicine and cellular longevity (2021)

ROS mediate the vasoconstrictor response within the cold-induced vascular response, and ROS in blood vessel tissues rather than nerve fibers are involved in vasoconstriction via the ROS/RhoA/ROCK1 and ROS/PKC/ET-1 pathways in VSMCs and endothelial cells.

Keyphrases

reactive oxygen species
cell death
dna damage
endothelial cells
high glucose
gene expression
diabetic rats
drug induced