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A new sesquiterpenoid from the aconitum -derived fungus Aspergillus fumigatus M1.

Hao DingJia-Peng WangSi-Ping DengJun-Li GanBing-Xian LiLing-Ling YaoSheng-Qi ZhangLe CaiZhong-Tao Ding
Published in: Natural product research (2022)
A new bergamotane sesquiterpenoid, fumigatanol ( 1 ), along with nine known compounds ( 2 - 10 ) were isolated from the Aconitum -derived fungus Aspergillus fumigatus M1. Their structures were established on the basis of extensive spectroscopic analyses, ECD experiment and NMR computational method. Antibacterial and cytotoxic activities of compound 1 were evaluated and no obvious antibacterial and cytotoxic activities were observed at concentrations of 256 μg/mL and 40.00 μM, respectively.
Keyphrases
  • high resolution
  • silver nanoparticles
  • magnetic resonance
  • molecular docking
  • anti inflammatory
  • essential oil
  • solid state
  • cell wall