TNFα and IFNγ rapidly activate PI3K-AKT signaling to drive glycolysis that confers mesenchymal stem cells enhanced anti-inflammatory property.
Chenchang XuChao FengPeiqing HuangYinghong LiRui LiuChunxiao LiuYuyi HanLei ChenYayun DingChangshun ShaoYufang ShiPublished in: Stem cell research & therapy (2022)
The glycolysis-dependent anti-inflammatory property of MSCs conferred by inflammatory cytokines is mediated by PI3K-AKT signaling pathway.