Duration of immune protection of SARS-CoV-2 natural infection against reinfection.
Hiam ChemaitellyNico NagelkerkeHoussein H AyoubPeter CoylePatrick TangHadi M YassineHebah A Al-KhatibMaria K SmattiMohammad R HasanZaina Al-KanaaniEinas Al-KuwariAndrew JeremijenkoAnvar Hassan KaleeckalAli Nizar LatifRiyazuddin Mohammad ShaikHanan F Abdul-RahimGheyath K NasrallahMohamed Ghaith Al-KuwariAdeel Ajwad ButtHamad Eid Al-RomaihiMohamed H Al-ThaniAbdullatif Al-KhalRoberto BertolliniLaith Jamal Abu-RaddadPublished in: Journal of travel medicine (2022)
Protection of natural infection against reinfection wanes and may diminish within a few years. Viral immune evasion accelerates this waning. Protection against severe reinfection remains very strong, with no evidence for waning, irrespective of variant, for over 14 months after primary infection.