Investigation of INDEL variants in apoptosis: the relevance to gastric cancer.

Giovanna Chaves CavalcanteMilene Raiol de MoraesCristina Maria Duarte ValenteCaio Santos SilvaAntônio André Conde ModestoPaula Baraúna de AssumpçãoPaulo Pimentel de AssumpçãoSidney SantosÂndrea Kely Campos Ribeiro Dos Santos

Published in: BMC medical genetics (2020)

Our results suggest that rs4197 (FADD gene) might play a role in gastric carcinogenesis in the investigated population. More studies are needed to clarify this relation. Here, we highlight the importance of investigating INDEL variants in genes involved in apoptosis.

Keyphrases

copy number
endoplasmic reticulum stress
cell cycle arrest
oxidative stress
cell death
genome wide
dna methylation
mass spectrometry
high resolution
case control
genome wide identification