Serum P-glycoprotein level: a potential biomarker of DMARD failure in patients with rheumatoid arthritis.

Perez-Guerrero Edsaul Emilio Gonzalez-Lopez Laura José Francisco Munoz-Valle Jose C Vasquez-Jimenez Melissa Ramirez-Villafaña Esther N Sanchez-Rodriguez Sergio R Gutierrez Urena Sergio Cerpa-Cruz E A Aguilar-Chavez Ernesto German Cardona Muñoz Maria Luisa Vazquez-Villegas Saldaña-Cruz Ana Miriam Norma Alejandra Rodriguez-Jimenez Nicte S Fajardo-Robledo Jorge Ivan Gamez-Nava

Published in: Inflammopharmacology (2018)

Elevated serum P-gp is associated with DMARD failure. The P-gp level can be considered a clinical tool for evaluating the risk of DMARD failure in patients; however, future prospective studies should be performed to evaluate the utility of this marker in predicting long-term responses.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
current status
patient reported