Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy.
Viviana CasagrandeGiulia IulianiStefano MeniniGiuseppe PuglieseMassimo FedericiRossella MenghiniPublished in: Clinical and translational medicine (2021)
In diabetic mice the targeting of TIMP3 system improved kidney structure and function, representing a valid approach to develop new avenues to treat this severe complication of diabetes.