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Increased urinary excretion of kynurenic acid is associated with non-recovery from acute kidney injury in critically ill patients.

Fabienne AreggerDominik E UehlingerGerhard FuschAldin BahonjicRene PschowskiMichael WalterJoerg C Schefold
Published in: BMC nephrology (2018)
Increased urinary levels of kynurenic acid, a key inflammatory metabolite of the tryprophan degradation pathway, are associated with adverse renal and clinical outcomes in critically ill patients with AKI. Urinary KynA may serve as an early risk stratificator in respective patients with AKI.
Keyphrases
  • acute kidney injury
  • oxidative stress
  • emergency department
  • adverse drug
  • electronic health record