Known pathogenic gene variants and new candidates detected in Sudden Unexpected Infant Death (SUID) using Whole Genome Sequencing (WGS).
Angela M BardLindsay V ClarkErdal CosgunKimberly A AldingerAndrew TimmsLely A QuinaJuan M Lavista FerresDavid JardineElisabeth A HaasTatiana M BeckerChelsea M PaganAvni SantaniDiego MartinezSoumitra BaruaZakkary McNuttAddie NesbittJan-Marino RamirezPublished in: medRxiv : the preprint server for health sciences (2023)
Our study confirms and further expands the list of genetic variants associated with SUID. The abundance of genes associated with heart disease and the discovery of variants associated with the redox metabolism has important mechanistic implications for the pathophysiology of SUID.