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Membranous nephropathy in a female patient with X-linked thrombocytopenia.

Mari OkadaMasayuki NagasawaAkihiro OshibaHiroyuki Kawaguchi
Published in: Pediatric nephrology (Berlin, Germany) (2022)
To our knowledge, this is the first report of MN in a female WAS/XLT patient. WAS protein expression defects affect all immune system cells; however, the mechanisms underlying the occurrence of autoimmunity are not completely understood. In WAS/XLT patients, MN may develop as a result of increased autoantibody production, similar to other types of immunodeficiency.
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