Membranous nephropathy in a female patient with X-linked thrombocytopenia.
Mari OkadaMasayuki NagasawaAkihiro OshibaHiroyuki KawaguchiPublished in: Pediatric nephrology (Berlin, Germany) (2022)
To our knowledge, this is the first report of MN in a female WAS/XLT patient. WAS protein expression defects affect all immune system cells; however, the mechanisms underlying the occurrence of autoimmunity are not completely understood. In WAS/XLT patients, MN may develop as a result of increased autoantibody production, similar to other types of immunodeficiency.