Genetic polymorphism in Methylenetetrahydrofolate Reductase chloride transport protein 6 ( MTHFR CLCN6 ) gene is associated with keratinocyte skin cancer in a cohort of renal transplant recipients.

Laoise R GriffinL HoR J AkhurstS T ArronJennifer M E BoggsP ConlonP O'KellyAmanda Ewart TolandE H EpsteinA BalmainB C BastianF J MoloneyG M MurphyM E Laing

Published in: Skin health and disease (2022)

is not known, it is proposed to be involved in folate availability. Future applications could include incorporation in a polygenic risk score for KC in RTRs to help identify those at increased risk beyond traditional risk factor assessment.

Keyphrases

skin cancer
genome wide
copy number
risk factors
current status
dna methylation
protein protein
amino acid
genome wide identification
binding protein
small molecule
transcription factor