Utility of CD4 count measurement in the era of universal antiretroviral therapy: an analysis of routine laboratory data in Botswana.
Tshepo LeemeM MineK LechiileF MulengaM MosepeleT MphoyakgosiC MuthogaJ NgidiB NkomoD RamaabyaM TauM W TenfordeR HayesJ N JarvisPublished in: HIV medicine (2020)
One-quarter of HIV-positive individuals in Botswana still present with advanced HIV disease, highlighting the importance of baseline CD4 count measurement to identify this at-risk population. Few with a baseline CD4 count ≥ 200 cells/µL experienced a drop below 200 cells/µL, suggesting limited utility for ongoing CD4 monitoring.
Keyphrases
- hiv positive
- antiretroviral therapy
- hiv infected
- men who have sex with men
- human immunodeficiency virus
- induced apoptosis
- hiv aids
- hiv infected patients
- south africa
- cell cycle arrest
- peripheral blood
- hiv testing
- nk cells
- hepatitis c virus
- endoplasmic reticulum stress
- big data
- signaling pathway
- machine learning
- deep learning
- artificial intelligence