NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling.

Enchong ZhangZhengjie ChenWangmin LiuLin LinLina WuJohnny GuanJianfeng WangChuize KongJianbin BiMo Zhang

Published in: Journal of translational medicine (2024)

NCAPG2 is highly expressed in PCa, and its level is significantly associated with PCa prognosis. NCAPG2 promotes PCa malignancy and drives cancer stemness via the STAT3/c-MYC signaling axis, highlighting its potential as a therapeutic target for PCa.

Keyphrases

prostate cancer
stem cells
epithelial mesenchymal transition
cell proliferation
papillary thyroid
squamous cell
squamous cell carcinoma
lymph node metastasis
young adults
childhood cancer