The Identification and Clinical Applications of Mutated Antigens in the Era of Immunotherapy.

Yae KyeLokesh NagineniShrikanth S GadadFabiola RamirezHannah RivaLorena FernandezMichelle SamaniegoNathan HollandRose YehKei TakigawaSubramanian DhandayuthapaniJessica Chacon

Published in: Cancers (2022)

The era of personalized cancer therapy is here. Advances in the field of immunotherapy have paved the way for the development of individualized neoantigen-based therapies that can translate into favorable treatment outcomes and fewer side effects for patients. Addressing challenges related to the identification, access, and clinical application of neoantigens is critical to accelerating the development of individualized immunotherapy for cancer patients.

Keyphrases

cancer therapy
end stage renal disease
ejection fraction
newly diagnosed
drug delivery
prognostic factors
bioinformatics analysis
dendritic cells
immune response
patient reported outcomes
wild type