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Hurthle cell carcinoma in childhood: A retrospective analysis of five cases and review of pediatric literature.

Giuseppina ZirilliMariella ValenziseGianlorenzo DionigiGiovanni TuccariCarmelo RomeoAlfredo CampennìAndrea CorriasGerdi TuliAntonio IeniGiovanni Battista PajnoMalgorzata Gabriela Wasniewska
Published in: Pediatric blood & cancer (2020)
(1) In childhood, the relative prevalence of HCC among different thyroid cancer histotypes is 5.8%, that is close to the one previously reported both in the general population and in other less numerous children's cohorts; (2) HCC may develop even early, at the age of 7; (3) in childhood, HCC does not seem to have a more aggressive behavior when compared with other DTC histotypes; (4) antecedents of other diseases are not infrequent in the history of children with HCC.
Keyphrases
  • childhood cancer
  • young adults
  • early life
  • systematic review
  • risk factors