Mouse pharmacokinetics and metabolism of the phenylurea thiocarbamate NSC 161128.

Emily J KoubekRachel A KudgusChad A WaldenRenee M McGovernJoseph M CoveyMatthew M AmesJoel M Reid

Published in: Cancer chemotherapy and pharmacology (2022)

An analytical LC-MS/MS method was successfully developed for the detection and quantification of NSC 161128 and its metabolites. These results increase the understanding of NSC 161128 pharmacokinetic and metabolic properties.

Keyphrases

ms ms
label free
real time pcr
liquid chromatography
mass spectrometry
sensitive detection