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Higher cefazolin concentrations in synovial fluid with intraosseous regional prophylaxis in knee arthroplasty: a randomized controlled trial.

Jingyu ZhangGuangxiang ChenXiao YuYubo LiuZhiqiang LiXiangxin ZhangQiao ZhongRenjie Xu
Published in: Archives of orthopaedic and trauma surgery (2023)
Intraosseous regional administration results in several times higher tissue concentrations than systemic administration, especially in the synovial fluid.
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