Real-world causal evidence for planned predictive enrichment in critical care trials: A scoping review.

Benjamin Skov Kaas-Hansen Anders Granholm Praleene Sivapalan Carl Thomas Anthon Olav Lilleholt Schjørring Mathias Maagaard Maj-Brit Nørerregaard Kjaer Jesper Mølgaard Karen Louise Ellekjaer Steen Kåre FagerbergTheis LangeMorten Hylander Möller Anders Perner

Published in: Acta anaesthesiologica Scandinavica (2023)

Work is needed to harness the rich multiverse of critical care data and establish its utility in critical care RCTs. Such work will likely need to leverage methodology from interventional and analytical epidemiology as well as data science.

Keyphrases

electronic health record
big data
public health
risk factors
mass spectrometry
deep learning