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Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker.

Guido Alessandro BaselliPaola DongiovanniRaffaela RamettaMarica MeroniSerena PelusiMarco MaggioniSara BadialiPiero PingitoreSamantha MaurottiTiziana MontalciniAlice Emma TalientoDaniele PratiGiorgio RossiAnna Ludovica FracanzaniRosellina Margherita MancinaStefano RomeoLuca Vittorio Valenti
Published in: Gut (2020)
Hepatic IL32 is overexpressed in NAFLD, correlates with hepatic fat and liver damage, and is detectable in the circulation, where it is independently associated with the presence and severity of NAFLD.
Keyphrases
  • adipose tissue
  • single cell
  • oxidative stress