What role does metal allergy sensitization play in total knee arthroplasty revision?
David R LionbergerJustin SamorajskiCharlie D WilsonAndreana RiveraPublished in: Journal of experimental orthopaedics (2018)
This study provides objective data via histological analysis in support of a nickel allergic sensitization in failed arthroplasties where clinical and/or radiographic abnormalities may not be apparent. Biopsy for CD4+/CD8+ cell counts may provide further proof of the existence of nickel sensitization in lymphocyte stimulation test positive patients, and more importantly, may implore the surgeon to consider low nickel implant design in these patients.
Keyphrases
- total knee arthroplasty
- end stage renal disease
- chronic kidney disease
- ejection fraction
- prognostic factors
- peritoneal dialysis
- stem cells
- magnetic resonance imaging
- magnetic resonance
- reduced graphene oxide
- peripheral blood
- cell therapy
- minimally invasive
- atopic dermatitis
- oxide nanoparticles
- metal organic framework
- infectious diseases