Non-missense variants of KCNH2 show better outcomes in type 2 long QT syndrome.

Takanori Aizawa Yuko Wada Kanae Hasegawa Hai Huang Tomohiko Imamura Jingshan Gao Asami Kashiwa Hirohiko Kohjitani Megumi Fukuyama Koichi Kato Eri Toda Kato Takashi Hisamatsu Seiko OhnoTakeru MakiyamaTakeshi Kimura Minoru Horie

Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)

Stratification based on molecular biological studies enables us to better predict clinical outcomes in the patients with LQT2.

Keyphrases

copy number
intellectual disability
case report
case control
drug induced
single molecule
metabolic syndrome
dna methylation
gene expression
glycemic control
insulin resistance