Autoregulation of Pax6 in neuronal cells is mediated by Pax6(5a), Pax6(ΔPD), SPARC, and p53.

Published in: Molecular biology reports (2022)

Our results suggest that autoregulation of Pax6 in neuronal cells is driven by a promoter dependent mechanism which is mediated by spliced variants [Pax6(5a) and Pax6(ΔPD)] and interacting proteins (SPARC and p53) of Pax6.

Keyphrases

induced apoptosis
cell cycle arrest
dna methylation
gene expression
transcription factor
oxidative stress
cell death
endoplasmic reticulum stress
cell proliferation
signaling pathway
copy number
cerebral blood flow
pi k akt
cerebral ischemia