Accelerated hippocampal biological aging in bipolar disorder.

Gabriel Rodrigo FriesIsabelle E BauerGiselli ScainiSamira S ValvassoriConsuelo Walss-BassJair C SoaresJoao Quevedo

Published in: Bipolar disorders (2019)

Hippocampal aging may underlie neurocognitive dysfunctions observed in BD patients. Moreover, our results suggest a complex cross-talk between biological clocks in hippocampus that may underlie clinical manifestations of premature aging in BD.

Keyphrases

bipolar disorder
end stage renal disease
ejection fraction
newly diagnosed
cerebral ischemia
major depressive disorder
peritoneal dialysis
brain injury
temporal lobe epilepsy