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Multicolor sparse viral labeling and 3D digital tracing of enteric plexus in mouse proximal colon using a novel adeno-associated virus capsid.

Lixin WangCollin ChallisSonglin LiCharless C FowlkesSripriya Ravindra KumarPu-Qing YuanYvette F Taché
Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
The multicolor AAV-PHP.S-packaged vectors enabled random sparse spectral labeling and revealed complexities of enteric microcircuit in the mouse proximal colon. The techniques can facilitate digital modeling of enteric micro-circuitry.
Keyphrases
  • gene therapy
  • flow cytometry
  • neural network
  • optical coherence tomography
  • single cell
  • ultrasound guided
  • computed tomography
  • dual energy
  • contrast enhanced