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Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19.

Sascha N GoonewardenaQinzhong ChenAshley M TateOlga G GrushkoDilna DamodaranPennelope K BlakelySalim Salim HayekDavid J PinskyRobert S Rosenson
Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Taken together, these observations further elucidate the pathological mechanisms that underlie immune dysfunction and coagulation abnormalities in COVID-19, contributing to our growing understanding of SARS-CoV-2 infections that could also be leveraged to develop novel diagnostic and therapeutic strategies.
Keyphrases
  • sars cov
  • coronavirus disease
  • respiratory syndrome coronavirus
  • dendritic cells
  • oxidative stress
  • endothelial cells