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Genetic variability in Iranian limb-girdle muscular dystrophy type 2B patients: An evidence of a founder effect.

Marzieh MojbafanShirzadeh TinaFatemeh Zafarghandi MotlaghAndrei SurguchovYalda NilipourSirous Zeinali
Published in: Molecular genetics & genomic medicine (2019)
Two of the other six families are from the same ethnicity and share the same mutation and haplotype patterns, suggesting a founder mutation. Genetic analysis of dysferlinopathy can prevent a wrong diagnosis of myositis for these patients.
Keyphrases
  • end stage renal disease
  • muscular dystrophy
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • peritoneal dialysis