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Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis.

Liam J O'NeilChristopher B OliveiraXinghao WangMario NavarreteAna Barrera-VargasJavier Merayo-ChalicoRwan AljahdaliEduardo Aguirre-AguilarPhilip M CarlucciMariana J KaplanCarmelo Carmona-Rivera
Published in: Annals of the rheumatic diseases (2023)
Our results suggest that NETs have a direct role in RA-associated bone erosion by promoting osteoclast formation.
Keyphrases
  • rheumatoid arthritis
  • bone loss
  • disease activity
  • ankylosing spondylitis
  • interstitial lung disease
  • bone mineral density
  • systemic lupus erythematosus
  • systemic sclerosis
  • postmenopausal women
  • bone regeneration