High versus Medium Dose of Inhaled Corticosteroid in Chronic Obstructive Lung Disease: A Systematic Review and Meta-Analysis.
Paraschos Archontakis BarakakisThuonghien TranJee Young YouGabriel J Hernandez RomeroVipul GidwaniFernando J MartinezSpyridon FortisPublished in: International journal of chronic obstructive pulmonary disease (2023)
Our study collected RCTs investigating the optimal dosing level of ICS prescribed alongside ancillary bronchodilators to patients with COPD. We identified that the high ICS dose neither reduces AECOPD risk and mortality rates nor increases pneumonia risk relative to the medium dose.