Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition.

Gilar Gorji-BahriB Madhu KrishnaCatharina HagerlingAkira OrimoKarin JirströmKonstantinos S PapadakosAnna M Blom
Published in: Journal of translational medicine (2024)
This study suggests that COMP secretion by CAFs drives ovarian cancer progression through the induction of the Notch pathway and epithelial-to-mesenchymal transition.