Th2-skewed peripheral T helper cells drives B cells in allergic bronchopulmonary aspergillosis.

Rong-Guang LuoYi-Fan WuHai-Wen LuDong WengJia-Yan XuLe-Le WangLi-Sha ZhangCai-Qi ZhaoJian-Xiong LiYong YuXin-Ming JiaJin-Fu Xu

Published in: The European respiratory journal (2024)

We identified a distinctly elevated population of circulating Th2-skewed Tph cells that induced the production of IgE in ABPA patients. It may be a biomarker and therapeutic target for ABPA.

Keyphrases

induced apoptosis
cell cycle arrest
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
endoplasmic reticulum stress
prognostic factors
cell death
peritoneal dialysis
oxidative stress
high glucose
regulatory t cells
dendritic cells
pi k akt
patient reported outcomes