Thrombotic microangiopathy with transiently positive direct Coombs test in an adult with poststreptococcal acute glomerulonephritis: a case report.
Dan InoueTakashi OdaSachiko IwamaTakahiko HoshinoMitsuya MukaeTakashi SakaiAki KojimaTakahiro UchidaTadasu KojimaKentaro SugisakiTomohiro TomiyasuNoriko YoshikawaMuneharu YamadaPublished in: BMC nephrology (2022)
These findings suggest that 2 pathogenic proteins of Streptococcus pyogenes, i.e., NAPlr and neuraminidase, induced glomerular lesions of PSAGN and tubulointerstitial inflammation with TMA, respectively, resulting in severe acute kidney injury in this patient.