Combined GSTT1 Null, GSTM1 Null and XPD Lys/Lys Genetic Polymorphisms and Their Association with Increased Risk of Chronic Myeloid Leukemia.
Ezeldine K AbdalhabibDenise E JacksonBadr AlzahraniElyasa M ElfakiAlneil HamzaFehaid AlanaziElryah I AliAbdulrahman AlgarniIbrahim Khider IbrahimMuhammad SaboorPublished in: Pharmacogenomics and personalized medicine (2021)
In conclusion, GSTT1 null, GSTM1 null and XPD polymorphisms showed positive association with the risk of development of CML. Furthermore, age and gender did not exhibit any association with the studied polymorphisms, while CML phases were associated with GSTT1 null polymorphism.
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