Transforming growth factor-β and matrix metalloproteinases as potential biomarkers of fibrotic lesions induced by tuberculosis: a systematic review and meta-analysis.
Arif SantosoRasiha RasihaAhmad Taufik Fadillah ZainalIndah Nurul KhairunnisaMuthia Kintan FaisAndi Muh Aunul Khaliq GunawanPublished in: BMJ open (2023)
There were differences in the results of TGF-β levels in patients with fibrotic lesions compared with controls. TGF-β might be a biomarker of fibrotic tissue formation or increased pulmonary tissue fibrosis in post-TB patients. However, further studies are needed on a larger scale.
Keyphrases
- transforming growth factor
- epithelial mesenchymal transition
- systemic sclerosis
- end stage renal disease
- idiopathic pulmonary fibrosis
- mycobacterium tuberculosis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- hiv aids
- pulmonary tuberculosis
- hepatitis c virus
- liver fibrosis