Elevated plasma levels of plasminogen activator inhibitor-1 are associated with risk of future incident venous thromboembolism.

Tobias FrischmuthKristian HindbergPål AukrustThor Ueland Sigrid Kufaas BrækkanJohn-Bjarne HansenVânia M Morelli

Published in: Journal of thrombosis and haemostasis : JTH (2022)

Our findings indicate that plasma PAI-1 is associated with increased risk of future incident VTE and has the potential to partially mediate the VTE risk in obesity.

Keyphrases

venous thromboembolism
direct oral anticoagulants
current status
cardiovascular disease
metabolic syndrome
insulin resistance
type diabetes
weight loss
weight gain
high fat diet induced
adipose tissue
risk assessment