A network-based approach for identifying suitable biomarkers for oral immunotherapy of food allergy.
Jolanda H M van BilsenLars VerschurenLaura WagenaarMarlotte M VonkBetty C A M van EschLéon M J KnippelsJohan GarssenJoost J SmitRaymond H H PietersTim J van den BroekPublished in: BMC bioinformatics (2019)
Here we provide a promising application of computational approaches to a) compare mechanistic features of two different food allergies during OIT b) determine the biological relevance of candidate biomarkers c) generate new hypotheses to explain why CMA has a different disease pattern than PNA and d) select relevant biomarkers for future studies.