Follow-up analysis of voice quality in patients with late-onset Pompe disease.

Krzysztof SzklannyAnna Tylki-Szymańska
Published in: Orphanet journal of rare diseases (2018)
The results suggest increased muscle weakness and progression of LOPD. The parameters Closed Quotient (calculated on the basis of an electroglottographic signal) and Peak Slope (calculated on the basis of an acoustic signal) proved to be the most sensitive.