Epithelial folliculin enhances airway inflammation in aspirin-exacerbated respiratory disease.
Hoang Kim Tu TrinhDuy Le PhamYoungwoo ChoiHyun-Mi KimSeung-Hyun KimHae-Sim ParkPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)
Our findings suggest that high LT and airway eosinophilia increased FLCN release from HAECs, which enhance epithelial activation and disruption. Modulation of FLCN may be a potential target for AERD.