Fertility Sparing Treatment in Gastric-Type Endocervical Carcinoma.
Agnieszka RychlikDenis QuerleuMariusz BidzinskiPublished in: Cancers (2021)
Fertility sparing management of cancer is one of the main components of quality-of-life issues. Early-stage cervical cancer, frequently diagnosed in women of reproductive age, can potentially be treated conservatively. However, some rare histological types of cervical cancer present with aggressive clinical behavior. Particularly, in the newly introduced concept of gastric-type endocervical carcinoma, fertility sparing management is 'a priori' not recommended. Even so, this issue remains undocumented. For this reason, a selected review of the current literature on gastric type endocervical carcinoma was carried out through PubMed. The keywords included "gastric-type cervical cancer", "gastric-type endocervical carcinoma", "conservative surgery", "conservative treatment", "fertility sparing surgery", "radical trachelectomy", "laparoscopic trachelectomy", "robotic trachelectomy", "laparotomic trachelectomy", "abdominal trachelectomy", "trachelectomy", "neoadjuvant chemotherapy", "conisation", and "cone resection". A search in the European Network on Cancer, Infertility and Pregnancy (INCIP) database was performed. The rarity of gastric-type endocervical carcinoma does not allow for conclusions on fertility sparing management with solid evidence. However, diffuse character of the disease and aggressive clinical behavior contraindicate a conservative treatment in young women with gastric type cervical cancer.
Keyphrases
- robot assisted
- neoadjuvant chemotherapy
- minimally invasive
- early stage
- systematic review
- childhood cancer
- type diabetes
- papillary thyroid
- emergency department
- radiation therapy
- lymph node
- combination therapy
- skeletal muscle
- polycystic ovary syndrome
- atrial fibrillation
- squamous cell
- locally advanced
- pregnancy outcomes
- sentinel lymph node
- low grade
- percutaneous coronary intervention
- drug induced
- lymph node metastasis