Aqueous extract of Platycodon grandiflorus attenuates lipopolysaccharide-induced apoptosis and inflammatory cell infiltration in mouse lungs by inhibiting PI3K/Akt signaling.
Yang ZhouTianzi JinMingtong GaoZichen LuoSadaf MutahirChen ShiTong XieLili LinJianya XuYingzhao LiaoMing ChenHaishan DengMin ZhengJin Jun ShanPublished in: Chinese medicine (2023)
The study revealed that the PAE attenuates lipopolysaccharide-induced apoptosis and inflammatory cell infiltration in mouse lungs by inhibiting PI3K/Akt signaling. Furthermore, our findings provide a novel strategy for the application of PAE as a potential agent for preventing patients with ALI.